scholarly journals β1-integrins dominate cell traffic of leukemic cells in human bone-marrow stroma

1996 ◽  
Vol 66 (2) ◽  
pp. 225-233 ◽  
Author(s):  
Detlef Van der Velde-Zimmermann ◽  
Veronique A. J. Smits ◽  
Marina A. M. Verdaasdonk ◽  
Louk H. P. M. Rademakers ◽  
Naomi Werner ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Leukemic Cells ◽  
Bone Marrow Stroma ◽  
Β1 Integrins ◽  
Marrow Stroma

scholarly journals Bone marrow matrix modulation of HL-60 phenotype

Blood ◽  
1987 ◽  
Vol 70 (4) ◽  
pp. 1119-1123
Author(s):  
SD Luikart ◽  
JL Sackrison ◽  
CA Maniglia
Keyword(s):  
Bone Marrow ◽  
Stromal Cell ◽  
Cellular Proliferation ◽  
Phenotypic Expression ◽  
Leukemic Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Leukemic Cells ◽  
Nonspecific Esterase ◽  
Marrow Stroma

The initiation and maintenance of cellular differentiation for a variety of cell types has been shown to be influenced by the microenvironment. To investigate the influence of bone marrow stroma on leukemic cell differentiation, HL-60 human promyelocytic leukemia cells were grown in the presence of Triton-treated extracellular matrix derived from normal human bone marrow stromal cells. This bone marrow matrix microenvironment had a dramatic impact on the phenotypic expression of this malignant line. HL-60 cellular proliferation, morphology, nonspecific esterase activity, formation of Fc rosettes, and sensitivity to induction by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) were all influenced by the presence of matrix molecules. In contrast, stromal cell-conditioned media did not alter HL-60 phenotype. Thus, HL-60 cells appear to retain responsiveness to a human bone marrow stromal cell-derived matrix despite their ability to grow autonomously. Studies of the interaction of leukemic cells and marrow stroma in vitro may provide important information concerning the regulation of leukemic cell behavior.

Interleukin 4 alters human bone marrow stroma and modulates its interaction with hematopoietic progenitors

Stem Cells ◽  
1994 ◽  
Vol 12 (6) ◽  
pp. 638-649 ◽  
Author(s):  
A. Ferrajoli ◽  
M. Talpaz ◽  
N. G. Ordonez ◽  
E. R. Stanley ◽  
C. Hirsch-Ginsberg ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Interleukin 4 ◽  
Bone Marrow Stroma ◽  
Hematopoietic Progenitors ◽  
Marrow Stroma

Fibronectin Distribution in Human Bone Marrow Stroma: Matrix Assembly and Tumor Cell Adhesion via α5β1 Integrin

1997 ◽  
Vol 230 (1) ◽  
pp. 111-120 ◽  
Author(s):  
D. Van der Velde-Zimmermann ◽  
M.A.M. Verdaasdonk ◽  
L.H.P.M. Rademakers ◽  
R.A. De Weger ◽  
J.G. Van den Tweel ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Adhesion ◽  
Tumor Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Matrix Assembly ◽  
Tumor Cell Adhesion ◽  
Marrow Stroma ◽  
Α5β1 Integrin

An Enzyme-Histochemical Approach to the Study of the Human Bone-Marrow Stroma

1984 ◽  
Vol 71 (2) ◽  
pp. 73-80 ◽  
Author(s):  
Vito L. Burgio ◽  
Umberto Magrini ◽  
Laura Ciardelli ◽  
Gabriella Pezzoni
Keyword(s):  
Bone Marrow ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Marrow Stroma

scholarly journals Expression of proteoglycan core proteins in human bone marrow stroma

1999 ◽  
Vol 343 (3) ◽  
pp. 663 ◽  
Author(s):  
Karen P. SCHOFIELD ◽  
John T. GALLAGHER ◽  
Guido DAVID
Keyword(s):  
Bone Marrow ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Core Proteins ◽  
Marrow Stroma

scholarly journals Ethanol May Suppress Wnt/β-catenin Signaling on Human Bone Marrow Stroma Cells

2008 ◽  
Vol 466 (5) ◽  
pp. 1047-1053 ◽  
Author(s):  
Ching-Hua Yeh ◽  
Je-Ken Chang ◽  
Yan-Hsiung Wang ◽  
Mei-Ling Ho ◽  
Gwo-Jaw Wang
Keyword(s):  
Bone Marrow ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Marrow Stroma ◽  
Bone Marrow Stroma Cells

scholarly journals Development and Characterization of Conditionally Immortalized Osteoblast Precursor Cell Lines from Human Bone Marrow Stroma

1998 ◽  
Vol 13 (2) ◽  
pp. 205-217 ◽  
Author(s):  
Kevin C. Hicok ◽  
Thierry Thomas ◽  
Francesca Gori ◽  
David J. Rickard ◽  
Thomas C. Spelsberg ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Lines ◽  
Precursor Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Marrow Stroma ◽  
Osteoblast Precursor Cell

Human bone marrow stroma-dependent cell line MOLP-5 derived from a patient in leukaemic phase of multiple myeloma

2000 ◽  
Vol 109 (1) ◽  
pp. 54-63 ◽  
Author(s):  
Yoshinobu Matsuo ◽  
Hans G. Drexler ◽  
Chiharu Nishizaki ◽  
Akira Harashima ◽  
Shunichi Fukuda ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Cell Line ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Marrow Stroma ◽  
Dependent Cell ◽  
Marrow Stroma
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